Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-2 (of 2 Records) |
Query Trace: McElroy KL[original query] |
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Endurance, refuge, and reemergence of dengue virus type 2, Puerto Rico, 1986-2007
McElroy KL , Santiago GA , Lennon NJ , Birren BW , Henn MR , Munoz-Jordan JL . Emerg Infect Dis 2011 17 (1) 64-71 To study the evolution of dengue virus (DENV) serotype 2 in Puerto Rico, we examined the genetic composition and diversity of 160 DENV-2 genomes obtained through 22 consecutive years of sampling. A clade replacement took place in 1994-1997 during a period of high incidence of autochthonous DENV-2 and frequent, short-lived reintroductions of foreign DENV-2. This unique clade replacement was complete just before DENV-3 emerged. By temporally and geographically defining DENV-2 lineages, we describe a refuge of this virus through 4 years of low genome diversity. Our analyses may explain the long-term endurance of DENV-2 despite great epidemiologic changes in disease incidence and serotype distribution. |
West Nile virus from blood donors, vertebrates, and mosquitoes, Puerto Rico, 2007
Hunsperger EA , McElroy KL , Bessoff K , Colon C , Barrera R , Munoz-Jordan JL . Emerg Infect Dis 2009 15 (8) 1298-300 West Nile virus (WNV) was isolated from a human blood donor, a dead falcon, and mosquitoes in Puerto Rico in 2007. Phylogenetic analysis of the 4 isolates suggests a recent introduction of lineage I WNV that is closely related to WNV currently circulating in North America. |
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